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Grey's Anatomy is one of the longest-running medical dramas on TV. The show has been on the air for 18 seasons and has a passionate fan base. The show follows the lives of surgeons working in a fictional hospital called Grey Sloan Memorial. The show has won numerous awards, including a Golden Globe Award and a Screen Actors Guild Award. Grey's Anatomy is one of the longest-running medical dramas on television. The series has won numerous awards, including a Golden Globe Award for Best Television Series – Drama and a Peabody Award. It has been nominated for 39 Emmy Awards, winning 5 of them. The show has also been nominated for multiple Screen Actors Guild Awards, winning six times. Grey's Anatomy is one of the most popular medical dramas on TV with 18 seasons and still continuing. But how well do you know it? 120 Grey's Anatomy Trivia Questions and Answers Answer these trivia questions to find out how well you know the TV show, Grey’s Anatomy! 1. Who is the lead character in Grey’s Anatomy? Meredith Grey 2. What is the name of the hospital where Grey’s Anatomy is set, which memorializes two doctors killed in a plane crash? Grey Sloan Memorial Hospital 3. As of September 2022, how many seasons has Grey's Anatomy been on for? 18 Seasons 4. What was the title of the pilot episode of Grey's Anatomy? "A Hard Day's Night" 5. Who directed the pilot episode of Grey's Anatomy? Peter Horton 6. What is the name of Grey's Anatomy creator? Shonda Rhimes 7. Who was the winner of the first solo surgery of the class during the second year of residency? Bailey 8. Who died in the first season finale of Grey's Anatomy? Lexie 9. In what year did Grey's Anatomy win its first Emmy Award? 2006: Best Casting - Drama Series 10. Who sang the song "Chasing Cars" in the second season finale of Grey's Anatomy? Tommee Profitt & Fleurie 11. Who was Izzie Stevens' soulmate in Grey's Anatomy? Denny Duquette 12. What do Owen Hunt and Cristina Yang decide to do after the shooting at Seattle Grace Mercy West? Get Married 13. How does Derek Shepherd die? He was hit by a truck 14. Who was Addison Montgomery's mentor? Vivian Carlsmith 15. Who is the father of Callie's baby on Grey's Anatomy? Mark Sloan 16. Complete the following quote from Meredith Grey: "Knowing is better than wondering. Waking is better than sleeping, and even the biggest failure, even the worst..." "...beats the hell out of never trying." 17. Why does Dr. Owen Hunt fire Dr. Teddy Altman? To free her from the hospital where her husband died 18. Who is Nicky Evans half-sister? Amber Helen Karev 19. Who does Meredith Grey say, "you're my person" to? Cristina Yang 20. Which season finale was Cristina Yang's last episode on Grey's Anatomy? Season 10 21. Who stole the heart for Denny's transplant surgery? Izzie Stevens 22. What is the name of Meredith Grey's father? Thatcher Grey 23. What is the name of Meredith Grey's mother? Ellis Grey 24. What is the name of Derek Shepherd's sister? Amelia Shepherd 25. What is the name of Cristina Yang's stepfather? Saul Rubenstein 26. Who was the first intern to die on Grey's Anatomy? Dr. Heather Brooks 27. Who was the first main character to die on Grey's Anatomy? Ellis Grey 28. As of September 2022, how many episodes of Grey's Anatomy have aired? 400 29. Who was the showrunner for Season 1 to 3 of Grey's Anatomy? Shonda Rhimes 30. Who has been the Grey's Anatomy showrunner for Season 4 to the present? Krista Vernoff 31. What is Meredith Grey's middle name? Ellis 32. What is Derek Shepherd's middle name? Christopher 33. What is Owen Hunt's sisters' names? Megan Hunt 34. How did George O'Malley die? He was hit by a bus 35. What type of cancer was Izzie Stevens diagnosed with? Metastatic melanoma 36. What causes a patient to assault Meredith and leave her barely conscious on the floor? A post-seizure hyper-aggression 37. Who leaves Seattle Grace Mercy West Hospital for another hospital in Minnesota in an attempt to run away from their problems, but would eventually return? Cristina 38. What is the name of the hospital that resulted from the merger of Seattle Grace Hospital and Mercy West Medical Center? Seattle Grace Mercy West Hospital 39. How does Lexie Grey die? In a plane crash 40. Who also dies in the plane crash with Lexie Grey? Mark 41. When Derek is left brain dead after being hit by a semi, who turns off the machines and allows him to die? Meredith 42. Who is Meredith Grey's half-sister? Lexie Grey 43. How many children does Meredith Grey have? Three 44. Which season finale does April and Matthew get married in? Season 14 45. Jackson Avery and Maggie Pierce get married in which season finale? Season 17 46. Which actress' sudden departure in 2017 was a result of not asking Ellen Pompeo's permission to take Polaroids on set? Jerrika Hinton 47. In what year did Grey's Anatomy Premier? 2005 48. What is the title of the classic human anatomy textbook published in 1858 London, that inspired the title Grey's Anatomy? Gray's Anatomy 49. Which TV network debuted Grey's Anatomy? The American Broadcasting Company 50. What is the title of the original theme song to Grey's Anatomy? Cosy in the Rocket 51. What is the title of the second episode of the first season of Grey's Anatomy? The First Cut Is the Deepest 52. What is the name of Meredith Grey's stepmother? Susan Grey 53. Who was Derek Shepherd married to before their divorce in 2007? Addison Montgomery 54. What type of surgery does Meredith Grey specialize in? General Surgery 55. What is the name of the real location that is used for filming at Grey Sloan Memorial Hospital? Veterans Administration Sepulveda Ambulatory Care Center 56. Where does Cristina move to run Burke’s hospital? Zurich, Switzerland 57. How many seasons has Sandra Oh been on Grey's Anatomy? 10 seasons 58. Who plays Meredith Grey in the TV series? Ellen Pompeo 59. Who plays Derek Shepherd in the TV series? Patrick Dempsey 60. Who plays Cristina Yang in the TV series? Sandra Oh 61. Where does Addison decide to move to and join Oceanside Wellness, led by Sam and Naomi? Los Angeles 62. Derek Shepherd was the former Head of what, at Grey Sloan Memorial Hospital? Neurosurgery 63. When Amelia ran from her wedding with Meredith and Maggie, where did they go? The gas station 64. What is the name of Maggie's father? Richard Webber 65. Which character was killed off in Season 12? Dr. Derek Shepherd 66. How many children does Jo Wilson have? One 67. Which actress left the show at the end of Season 13? Jerrika Hinton 68. Which actress withdrew her Emmy nomination due to a feud with show creator Shonda Rhimes? Katherine Heigl 69. Who was the first female Chief of Surgery for Grey Sloan Memorial Hospital? Miranda Bailey 70. What was Meredith's nickname, derived from Greek mythology about a monstrous Gorgon who was mean and lived with snakes? Medusa 71. What is the name of the foundation that would replace the Harper Avery Foundation? The Catherine Fox Foundation 72. What was Meredith Grey's first surgery? An Appendectomy 73. How long was Derek Shepherd married to Addison Forbes for? Eleven years 74. What kind of surgeon was Maggie Pierce? Cardiothoracic Surgeon 75. Which actor would be dismissed after season 3 of Grey's Anatomy for allegedly using insensitive and offensive language on the set? Isaiah Washington 76. In what year did Derek and Meredith get married? 2009 77. What is the name of Seattle Grace's rival hospital? Mercy West Medical Center 78. What type of surgeon is April Kepner? A Trauma Surgeon 79. Which doctor was shot by a patient in season 6? Dr. Charles Percy 80. Who made the mistake that Izzie Stevens was fired for in Grey's Anatomy? Alex Karev 81. Who has served the most stints as Chief of Surgery? Richard Webber 82. Which actor was allegedly killed off from Grey's Anatomy due to friction with Ellen Pompeo and Shonda Rhimes? Patrick Dempsey 83. Jackson Avery was the former Head of what, at Grey Sloan Memorial Hospital? Plastic Surgery 84. Who is Bailey's husband? Ben Warren 85. What kind of surgeon is Owen Hunt? A Trauma Surgeon 86. What three actors have remained part of the Grey's Anatomy cast the longest? Ellen Pompeo, Chandra Wilson, and James Pickens Jr. 87. What actress played Lexie Grey? Chyler Leigh 88. In what month did Grey's Anatomy premiere? March 89. Which actress will come back in season 19 in a limited capacity, appearing in fewer episodes and narrating? Ellen Pompeo 90. What actor portrays Richard Webber in Grey's Anatomy? James Pickens Jr. 91. What is the name of the actor who plays Dr. George O'Malley? T. R. Knight 92. What is the title of the song playing in the background when Derek dies? "Into the Fire" 93. Who set the Grey Sloan Memorial Hospital on fire to save herself and a child? Stephanie Edwards 94. What actress played Maggie Pierce on the show? Kelly McCreary 95. Roughly, how much was Ellen Pompeo making in total per year playing Meredith Grey? $20 million 96. According to the Hollywood Reporter, what did a 10-year-old girl learn from Grey’s Anatomy that helped her save her mom's life? How to administer CPR 97. Who is the widow of Henry Burton? Teddy Altman 98. What is the name of the institute that was founded by Preston Burke after winning a Harper Avery? Klausman Institute for Medical Research 99. In what season do Jackson and April get married? Season 10 100. Bailey is the Chief of what department at Seattle Grace Mercy West Hospital? Chief of Surgery 101. How long was Holden McKee in a coma due to an accident that occurred when he was a firefighter? 16 years 102. How did Meredith's mother die? Heart attack 103. In which season did George O’Malley die? Season six 104. What was Lexie trapped under when she passed away? A piece of aircraft 105. Which season did Katherine Heigl leave the show? Season 6 106. Richard Webber is the Chief of Surgery at which hospital? Seattle Grace Mercy West Hospital 107. Who was Owen's first wife? Cristina Yang 108. Arizona Robbins was the former Head of what, at Grey Sloan Memorial Hospital? Fetal Surgery 109. Who is Catherine Avery's son? Jackson Avery 110. What is the name of Meredith and Derek's eldest daughter? Zola 111. How many brothers and sisters does Alex Karev have? Two 112. What was the name of the Addison Montgomery spin-off from Grey's Anatomy? Private Practice 113. What was the name of the Ben Warren spin-off from Grey's Anatomy? Station 19 114. What profession was Matthew Taylor? Paramedic 115. What actress played Dr. Erica Hahn? Brooke Smith 116. What actor plays Jackson Avery? Jesse Williams 117. What kind of surgeon is Teddy Altman? A Cardiothoracic Surgeon 118. What is the name of the episode where Derek gets back together with Meredith? Piece of My Heart 119. Where do Owen and Teddy get married? The Emerald City Bar 120. What is April and Jackson's baby diagnosed with during pregnancy? Osteogenesis Imperfecta type 2 Conclusion: Grey's Anatomy is one of the longest-running medical dramas on TV and has been captivating audiences since it first aired in 2005. With a talented cast and crew, the show has won numerous awards over the years and continues to enthrall fans with its gripping storylines. Whether you're a long-time fan or just getting started, we hope these trivia questions and answers have helped you test your Grey's Anatomy knowledge and learn more about your favorite characters and their lives at Grey Sloan Memorial Hospital. Who knows - maybe you'll even be able to answer some of the tougher questions next time!

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