Grey’s Anatomy is one of the longest-running medical dramas on TV. The show has been on the air for 18 seasons and has a passionate fan base. The show follows the lives of surgeons working in a fictional hospital called Grey Sloan Memorial. The show has won numerous awards, including a Golden Globe Award and a Screen Actors Guild Award.
- Grey’s Anatomy is one of the longest-running medical dramas on television.
- The series has won numerous awards, including a Golden Globe Award for Best Television Series – Drama and a Peabody Award.
- It has been nominated for 39 Emmy Awards, winning 5 of them.
- The show has also been nominated for multiple Screen Actors Guild Awards, winning six times.
Grey’s Anatomy is one of the most popular medical dramas on TV with 18 seasons and still continuing. But how well do you know it?
120 Grey’s Anatomy Trivia Questions and Answers
Answer these trivia questions to find out how well you know the TV show, Grey’s Anatomy!
1. Who is the lead character in Grey’s Anatomy?
Meredith Grey
2. What is the name of the hospital where Grey’s Anatomy is set, which memorializes two doctors killed in a plane crash?
Grey Sloan Memorial Hospital
3. As of September 2022, how many seasons has Grey’s Anatomy been on for?
18 Seasons
4. What was the title of the pilot episode of Grey’s Anatomy?
“A Hard Day’s Night“
5. Who directed the pilot episode of Grey’s Anatomy?
Peter Horton
6. What is the name of Grey’s Anatomy creator?
Shonda Rhimes
7. Who was the winner of the first solo surgery of the class during the second year of residency?
Bailey
8. Who died in the first season finale of Grey’s Anatomy?
Lexie
9. In what year did Grey’s Anatomy win its first Emmy Award?
2006: Best Casting – Drama Series
10. Who sang the song “Chasing Cars” in the second season finale of Grey’s Anatomy?
Tommee Profitt & Fleurie
11. Who was Izzie Stevens’ soulmate in Grey’s Anatomy?
Denny Duquette
12. What do Owen Hunt and Cristina Yang decide to do after the shooting at Seattle Grace Mercy West?
Get Married
13. How does Derek Shepherd die?
He was hit by a truck
14. Who was Addison Montgomery’s mentor?
Vivian Carlsmith
15. Who is the father of Callie’s baby on Grey’s Anatomy?
Mark Sloan
16. Complete the following quote from Meredith Grey: “Knowing is better than wondering. Waking is better than sleeping, and even the biggest failure, even the worst…”
“…beats the hell out of never trying.”
17. Why does Dr. Owen Hunt fire Dr. Teddy Altman?
To free her from the hospital where her husband died
18. Who is Nicky Evans half-sister?
Amber Helen Karev
19. Who does Meredith Grey say, “you’re my person” to?
Cristina Yang
20. Which season finale was Cristina Yang’s last episode on Grey’s Anatomy?
Season 10
21. Who stole the heart for Denny’s transplant surgery?
Izzie Stevens
22. What is the name of Meredith Grey’s father?
Thatcher Grey
23. What is the name of Meredith Grey’s mother?
Ellis Grey
24. What is the name of Derek Shepherd’s sister?
Amelia Shepherd
25. What is the name of Cristina Yang’s stepfather?
Saul Rubenstein
26. Who was the first intern to die on Grey’s Anatomy?
Dr. Heather Brooks
27. Who was the first main character to die on Grey’s Anatomy?
Ellis Grey
28. As of September 2022, how many episodes of Grey’s Anatomy have aired?
400
29. Who was the showrunner for Season 1 to 3 of Grey’s Anatomy?
Shonda Rhimes
30. Who has been the Grey’s Anatomy showrunner for Season 4 to the present?
Krista Vernoff
31. What is Meredith Grey’s middle name?
Ellis
32. What is Derek Shepherd’s middle name?
Christopher
33. What is Owen Hunt’s sisters’ names?
Megan Hunt
34. How did George O’Malley die?
He was hit by a bus
35. What type of cancer was Izzie Stevens diagnosed with?
Metastatic melanoma
36. What causes a patient to assault Meredith and leave her barely conscious on the floor?
A post-seizure hyper-aggression
37. Who leaves Seattle Grace Mercy West Hospital for another hospital in Minnesota in an attempt to run away from their problems, but would eventually return?
Cristina
38. What is the name of the hospital that resulted from the merger of Seattle Grace Hospital and Mercy West Medical Center?
Seattle Grace Mercy West Hospital
39. How does Lexie Grey die?
In a plane crash
40. Who also dies in the plane crash with Lexie Grey?
Mark
41. When Derek is left brain dead after being hit by a semi, who turns off the machines and allows him to die?
Meredith
42. Who is Meredith Grey’s half-sister?
Lexie Grey
43. How many children does Meredith Grey have?
Three
44. Which season finale does April and Matthew get married in?
Season 14
45. Jackson Avery and Maggie Pierce get married in which season finale?
Season 17
46. Which actress’ sudden departure in 2017 was a result of not asking Ellen Pompeo’s permission to take Polaroids on set?
Jerrika Hinton
47. In what year did Grey’s Anatomy Premier?
2005
48. What is the title of the classic human anatomy textbook published in 1858 London, that inspired the title Grey’s Anatomy?
Gray’s Anatomy
49. Which TV network debuted Grey’s Anatomy?
The American Broadcasting Company
50. What is the title of the original theme song to Grey’s Anatomy?
Cosy in the Rocket
51. What is the title of the second episode of the first season of Grey’s Anatomy?
The First Cut Is the Deepest
52. What is the name of Meredith Grey’s stepmother?
Susan Grey
53. Who was Derek Shepherd married to before their divorce in 2007?
Addison Montgomery
54. What type of surgery does Meredith Grey specialize in?
General Surgery
55. What is the name of the real location that is used for filming at Grey Sloan Memorial Hospital?
Veterans Administration Sepulveda Ambulatory Care Center
56. Where does Cristina move to run Burke’s hospital?
Zurich, Switzerland
57. How many seasons has Sandra Oh been on Grey’s Anatomy?
10 seasons
58. Who plays Meredith Grey in the TV series?
Ellen Pompeo
59. Who plays Derek Shepherd in the TV series?
Patrick Dempsey
60. Who plays Cristina Yang in the TV series?
Sandra Oh
61. Where does Addison decide to move to and join Oceanside Wellness, led by Sam and Naomi?
Los Angeles
62. Derek Shepherd was the former Head of what, at Grey Sloan Memorial Hospital?
Neurosurgery
63. When Amelia ran from her wedding with Meredith and Maggie, where did they go?
The gas station
64. What is the name of Maggie’s father?
Richard Webber
65. Which character was killed off in Season 12?
Dr. Derek Shepherd
66. How many children does Jo Wilson have?
One
67. Which actress left the show at the end of Season 13?
Jerrika Hinton
68. Which actress withdrew her Emmy nomination due to a feud with show creator Shonda Rhimes?
Katherine Heigl
69. Who was the first female Chief of Surgery for Grey Sloan Memorial Hospital?
Miranda Bailey
70. What was Meredith’s nickname, derived from Greek mythology about a monstrous Gorgon who was mean and lived with snakes?
Medusa
71. What is the name of the foundation that would replace the Harper Avery Foundation?
The Catherine Fox Foundation
72. What was Meredith Grey’s first surgery?
An Appendectomy
73. How long was Derek Shepherd married to Addison Forbes for?
Eleven years
74. What kind of surgeon was Maggie Pierce?
Cardiothoracic Surgeon
75. Which actor would be dismissed after season 3 of Grey’s Anatomy for allegedly using insensitive and offensive language on the set?
Isaiah Washington
76. In what year did Derek and Meredith get married?
2009
77. What is the name of Seattle Grace’s rival hospital?
Mercy West Medical Center
78. What type of surgeon is April Kepner?
A Trauma Surgeon
79. Which doctor was shot by a patient in season 6?
Dr. Charles Percy
80. Who made the mistake that Izzie Stevens was fired for in Grey’s Anatomy?
Alex Karev
81. Who has served the most stints as Chief of Surgery?
Richard Webber
82. Which actor was allegedly killed off from Grey’s Anatomy due to friction with Ellen Pompeo and Shonda Rhimes?
Patrick Dempsey
83. Jackson Avery was the former Head of what, at Grey Sloan Memorial Hospital?
Plastic Surgery
84. Who is Bailey’s husband?
Ben Warren
85. What kind of surgeon is Owen Hunt?
A Trauma Surgeon
86. What three actors have remained part of the Grey’s Anatomy cast the longest?
Ellen Pompeo, Chandra Wilson, and James Pickens Jr.
87. What actress played Lexie Grey?
Chyler Leigh
88. In what month did Grey’s Anatomy premiere?
March
89. Which actress will come back in season 19 in a limited capacity, appearing in fewer episodes and narrating?
Ellen Pompeo
90. What actor portrays Richard Webber in Grey’s Anatomy?
James Pickens Jr.
91. What is the name of the actor who plays Dr. George O’Malley?
T. R. Knight
92. What is the title of the song playing in the background when Derek dies?
“Into the Fire”
93. Who set the Grey Sloan Memorial Hospital on fire to save herself and a child?
Stephanie Edwards
94. What actress played Maggie Pierce on the show?
Kelly McCreary
95. Roughly, how much was Ellen Pompeo making in total per year playing Meredith Grey?
$20 million
96. According to the Hollywood Reporter, what did a 10-year-old girl learn from Grey’s Anatomy that helped her save her mom’s life?
How to administer CPR
97. Who is the widow of Henry Burton?
Teddy Altman
98. What is the name of the institute that was founded by Preston Burke after winning a Harper Avery?
Klausman Institute for Medical Research
99. In what season do Jackson and April get married?
Season 10
100. Bailey is the Chief of what department at Seattle Grace Mercy West Hospital?
Chief of Surgery
101. How long was Holden McKee in a coma due to an accident that occurred when he was a firefighter?
16 years
102. How did Meredith’s mother die?
Heart attack
103. In which season did George O’Malley die?
Season six
104. What was Lexie trapped under when she passed away?
A piece of aircraft
105. Which season did Katherine Heigl leave the show?
Season 6
106. Richard Webber is the Chief of Surgery at which hospital?
Seattle Grace Mercy West Hospital
107. Who was Owen’s first wife?
Cristina Yang
108. Arizona Robbins was the former Head of what, at Grey Sloan Memorial Hospital?
Fetal Surgery
109. Who is Catherine Avery’s son?
Jackson Avery
110. What is the name of Meredith and Derek’s eldest daughter?
Zola
111. How many brothers and sisters does Alex Karev have?
Two
112. What was the name of the Addison Montgomery spin-off from Grey’s Anatomy?
Private Practice
113. What was the name of the Ben Warren spin-off from Grey’s Anatomy?
Station 19
114. What profession was Matthew Taylor?
Paramedic
115. What actress played Dr. Erica Hahn?
Brooke Smith
116. What actor plays Jackson Avery?
Jesse Williams
117. What kind of surgeon is Teddy Altman?
A Cardiothoracic Surgeon
118. What is the name of the episode where Derek gets back together with Meredith?
Piece of My Heart
119. Where do Owen and Teddy get married?
The Emerald City Bar
120. What is April and Jackson’s baby diagnosed with during pregnancy?
Osteogenesis Imperfecta type 2
Conclusion:
Grey’s Anatomy is one of the longest-running medical dramas on TV and has been captivating audiences since it first aired in 2005. With a talented cast and crew, the show has won numerous awards over the years and continues to enthrall fans with its gripping storylines.
Whether you’re a long-time fan or just getting started, we hope these trivia questions and answers have helped you test your Grey’s Anatomy knowledge and learn more about your favorite characters and their lives at Grey Sloan Memorial Hospital. Who knows – maybe you’ll even be able to answer some of the tougher questions next time!
